Methods

Mini pigs were treated subdermally with two different lasers on both sides of the body. The cannula was placed through one incision point and passed through the tissue to create several individual laser channels. Five passes with equal spacing were made in each of several quadrants. Biopsies were excised after one day of treatment. Histological H&E stains were performed.

Laser Settings

980 nm Diode Laser Max Power output: 20 W Smartlipo MPX Laser Max Power Output: 30 W

Results

Histology stains after one day of treatment show small open channels surrounded with lysed adiposites and thermal coagulated septa. Slides from tissue treated with the Diode CW laser demonstrate more hemorrhaging or bleeding when compared to the tissue treated with the Smartlipo MPX Pulsed Laser. Additional bleeding is evidenced by the increased amount of red blood cells in the tissue.

How Do Different Pulse Durations Affect Bleeding During Laser Lipolysis?

Continuous wave laser results in more bleeding

Smartlipo MPX and the Theory of Selective Photothermolysis

Optimal use of the laser energy requires appropriate wavelengths, pulse duration and level of energy. Based on the theory of selective photothermolysis, the pulse duration must be shorter than the thermal relaxation time of the vessel to achieve effective vessel coagulation.* Due to the specific pulse duration of the Smartlipo MPX, it is more effective than continuous wave.

The high energy pulses from the MPX laser heat the vessel quickly, creating a much higher probability of vessel coagulation. The blood vessels exposed to the continuous wave laser continue to bleed since the temperature rises at a slower rate and the peak temperature is lower than that of the Smartlipo MPX.

1. The pulse structure of the Smartlipo MPX provides a shorter pulse duration than the thermal relaxation period.

2. Continuous wave does not provide the peak temperature level to achieve consistent coagulative effect.